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Villitis of unknown etiology, abbreviated VUE, is rare recurrent pathology of the placenta. Villitis of Unknown Etiology Chronic villitis is a relatively common pathologic finding usually in the third trimester placenta and has two distinct clinical associations: infectious and (apparently) non‐infectious. Additionally, the inflammation may spread to the chorionic villi, which cover the placenta and facilitate the exchange of nutrients and gases between the mother and baby. This is a condition called villitis, which is usually benign but can increase the risk of fetal death.

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It is a common lesion, affecting 5% to 15% of all placentas. When low-grade lesions affecting less than 10 villi per focus are excluded, VUE is an important cause of Placenta Pagina 1 van 33 Landelijke 3. Help tekst bij rubriek Chronische villitis van onbekende etiologie is aangepast Versie 15 (16-05-2018) 4. The prevalence of inflammatory villous lesions was determined in a prospective study of 120 consecutive placentas. Cord blood IgM level was measured as an indicator of fetal intrauterine infection, and the birthweights of the infants were noted. Ten cases of villitis were found.

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Conclusion: The clinically oriented, unifying and simple placental pathology classification system may work as a platform for  Morphological characteristics of Placenta in various conditions . finding was villitis basalis, which was noted in 7 placentas with high grade VUE and 4. 2 Mar 2020 The diagnosis of chronic villitis can be confirmed once a pathologist has examined the placenta after birth. Chronic intervillositis is a less  The origins of placental dysfunction are poorly understood.

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Villitis of unknown origin is believed to be a maternal inflammatory reaction against fetal antigens. Placenta; Villitis of unknown etiology Summary Villitis of unknown etiology (VUE) is an important pattern of placental injury occurring predominantly in term placentas.

Generally, there are no distinct signs and symptoms associated with Villitis of Unknown Etiology. The placenta may be small (low weight) for gestational age, otherwise it may look normal (grossly) There is no sign of infection in the mother 2006-06-01 · Villitis is not an unusual finding of microscopic examination of the placenta. However, even though an extensive workup for infectious causes has been done, most villitis cases are categorized as of unknown etiology. Villitis of unknown origin is believed to be a maternal inflammatory reaction against fetal antigens.
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In contrast to acute chorioamnionitis of infection-related origin, the fundamental immunopathology of VUE is unknown.

Can form microabscesses.
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2007-10-01 · Villitis of unknown etiology (VUE) is an important pattern of placental injury occurring predominantly in term placentas. Although overlapping with infectious villitis, its clinical and histologic characteristics are distinct. It is a common lesion, affecting 5% to 15% of all placentas. PubMed 2018-10-04 · What are the Signs and Symptoms of Villitis of Unknown Etiology?